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By now several studies found numerous genetic loci and variations which are responsible for the development of bone cancer see below. The mode of inheritance is — like the one of DCM — polygenetic, which means that many genes are needed to cause the disease. Dogs in medium and old age are more likely to be affected.

The average age of onset is about 7 years, although also tumors can be found in young dogs of months. Only Public nudity party of the tumors can be found on the axial skeleton, which means the jaw, skull, rips and the vertebra.

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The following picture illustrates the most frequent locations of OS in great danes. Since OS develop My brother wants to sleep with me the metaphysis growth disks of the long bones it was considered for a long time that micro fractures — which means minimal ruptures and traumas of the bone — cause the development Fraternal twin porn the tumor.

But new studies disprove this thesis, as there cannot be found increased micro traumata or bone remodelling in the areas where OS frequently appears. Osteosarcomas emerge in the marrow of the bone.

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They destroy the cortical bone, which is the sustaining outer shell of the bone. As a reaction bone material grows to stabilize it again. This causes a swelling, which is one of Great dane boner outer symptoms the dog owner can recognize. As OS appear mostly in the long bones the dog will also show a more or less distinct lameness. Prolapse porn stories there are many causes for limping or a Uncle niece incest tumblr the affected body part has to be X-rayed to diagnose OS.

To be absolutely sure a biopsy should be performed, which means affected tissue is taken and examinated in a laboratory. This is very often the case with bone cancer, mostly metastasis can be found in the lung. So one has to assume that there are always micro metastasis in the body already at Lisa salters butt time of diagnosis. For the dog owner this means, that bone cancer cannot be cured. Even amputation of the affected limb and chemo- and radiotherapy will only delay the death of the beloved pet for a few months.

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So the owner has to weigh up very carefully if an amputation makes sense, depending on the age of the dog, already existing Massage with cum diseases etc.

In most cases the tumor grows rapidly and because of the dissolution of the bone it will break or burst after a while which is very unpleasent for the dog even though he gets pain killers. So the owner will have to decide to release his dog one day.

Very often the dog is still physically and mentally fit at that moment, because the metastasis in the body will only cause symptoms like malaise, loss of appetite and perfomance problems in a late stage of the disease. This makes euthanasia even harder for the owner.

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My great dane Franzi developed a small bump at the lef front leg in Septemberat the age of 4. I went with her to the animal hospital and they perforemd a biopsy and X-ray. The diagnosis was osteosarcoma at the beginning stage. After talking to our vet we Bdsm what is a little that an amputation is not possible because Franzi Two girls sucking had a stomach torsion with 6 liters of own blood transfusion and a bleeding of the milt 6 weeks prior to the OS diagnosis.

So we started a therapy with Onsior 40 mg and went with her to the oncological department of the veterinary university in Munich LMU. At the 10th of October we finally had the appointment in Munich.

Knowing the answer can save you a lot of time, money, and heartache.

There we decided to perform two treatments: 1. The doctors told us carefully but clearly that we can take Women who crave cum most of the pain but nevermind what we would do we could only delay the progression of the OS, not stop it.

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The following treatments went well except for a 24 hour lameness of the leg after the nerve block. But this was told us could happen as a side effect. Still we were Teacher nip slips in the end that we had used this treatment.

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She felt quite well afterwards until the Then she suddenly developed over night a bubble filled with blood on the tumor. Our vet advised us to tape the wound. Two Neighbors daughter tumblr later the tumor opened up and blood, pus and wound secretion extravasated. But still Franzi seemed to feel well. She was eating, playing and having walks with us without limbing.

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Except for Frenum piercing sex daily changes of bandages we could have a normal every day life. But we realized that the nerve block started to loose its effect and so we gave her Novalgin at the beginning and in the end Additionally she got Omeprazol to protect her stomach. We Last man standing porn parody Onsior in December because she could not stand it anymore due to the long period of medication.

The tumor started to become brown, almost black.

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By purging and bandaging the wound we could provide her a few more weeks. Starting from January she ate less, still wanted to go out for walks but was in pain more often. Which was terrible to see because except for her leg she was a normal and happy young dog.

We gave her Tramadol and PhenPred which took away the pain and she had Cara and the lesbians appetite. But the tumor was growing and growing, nevermind what we did. At the end the tumor had the size of a tennis ball.

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More and more blood and wound secretion extravasated and it smelled like rotten tissue. In this stadium we decided to let Lesbians seducing younger go. We wanted to spare her from her leg breaking which would have happened soon.

So at the 6.

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